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Dr. Pradeep K. Karla

Department/ College

Pharmaceutical Sciences

E-mail:

pkarla@howard.edu

Phone:

2028066543

NAMES OF ANY COLLABORATOR(S):

NAME AND EMAIL ADDRESS OF NOMINEE'S DEPARTMENT CHAIR:

Dr. Muhammad J. Habib, mhabib@howard.edu

BIOSKETCH

EDUCATION:

Dr. Pradeep K. Karla completed his Bachelors in Pharmacy from Nagarjuna University, India in 2002. Dr. Karla later completed his Masters in Pharmaceutical Sciences in 2004 and Ph.D. in Pharmaceutics and Drug Design in 2008 respectively from the University of Missouri-Kansas City, USA.

POSITIONS AND SERVICE:

2009 - Current Assistant Professor, Howard University,
College of Pharmacy
Courses taught: Pharmaceutics,
Pharmaceutical Compounding Lab,
Biopharmaceutics, Pharmacokinetics,
Pharmaceutical Sciences Lab (Coordinator),
Introduction to Pharmacy and Pharmaceutical
Care
Ph.D. Mentor: Ann-Marie Ako-Adounvo
Class Advisor: Pharm.D. 2013 class
2011-Current NIH Clinical and Translational Research
Scholar (K12 Grant)
2011-Current Editor-Pharmaceutical Sciences – Chronicles
of Young Scientists Journal
2010-Current Editorial Board Member - Archives of
Pharmacy Practice, Pharmaceutics & Novel
Drug Delivery Systems and Journal of
Autocoids
2008-Current Reviewer - Journal of Controlled Release,
Pharmaceutical Research, Journal of
Ocular Pharmacology and Therapeutics,
Current Eye Research and Drug Dev. and
Industrial Pharmacy, Clinical Research and
Regulatory Affairs
2004-2007 Graduate Teaching Assistant - University of
Missouri-Kansas City, USA
Courses taught: Novel Drug Delivery Systems
and Pharmaceutics Lab
2003-2008 NIH Graduate Research Assistant -
University of Missouri-Kansas City, USA
HONORS:

2012 Appreciation Award – Pharmaceutics -
Pharm.D. Class 2015, College of Pharmacy,
Howard University
2011 Professor of the Year Award – Pharm.D.
Class 2014, College of Pharmacy,
Howard University
2011 First Place in Junior Faculty Category –
Howard University Health Sciences Research
Day
2010 Appreciation Award – Excellence in
Teaching, Mentoring and Enhancing
Pharmacy Education – Pharm.D. Class of
2013, College of Pharmacy
2010 Appreciation Award – Valuable Contributions
to Pharmacy Education – Pharm.D.
Class of 2012, College of Pharmacy
2009 AACP Outstanding research project – Recent
top discoveries in Pharmaceutical Research
2007 Scientific Sessions organizing committee Co-
chair, PGSRM Annual Meeting 2007

RESEARCH:

ACTIVE
K12 CTSA Grant (Karla PK - PI) 07/18/2011–07/18/2014 75% Effort - NIH - $407,646

Nanotherapeutic Mediated Efflux Modulation for Improved Ocular Drug Disposition – NIH-K12 Georgetown and Howard Universities Center for Clinical and Translational Research Grant

The major goal of this project is to develop a Chitosan-PLGA nano-ophthalmic formulation strategy for corneal drug efflux modulation and improved bioavailability. There is no scientific and budgetary overlap with the current proposal.

AACP New Investigator Award (Karla PK-PI)1/12/2012–1/13/2013 5% Effort - AACP - $9,700

Modulation of MRP Drug Efflux for Improved Ocular Drug Delivery

The major goal of this project is to study is to evaluate the role of MRP drug efflux pumps discovered on human corneal epithelium in affecting ocular bioavailability of glaucoma drugs. There is no scientific and budgetary overlap with the current proposal.

NSF-Major Instrumentation Grant (Karla PK - Collaborator)
09/01/2011 – 08/31/2014 - 3% Effort- NSF - $316,056

Acquisition of an Electrospray Mass Spectrometer for Chemical Research and Training

The major goal of this project is to procure accurate-mass time-of-flight liquid-chromatograph mass spectrometer (TOF-LC/MS) with electrospray ionization (ESI) capabilities. There is no scientific and budgetary overlap with the current proposal.

Travel Grant (Karla PK – PI)
5/01/2011 – 05/01/2013 - Howard University - $2,500

This grant is awarded for Securing First Position at Health Sciences Research Meeting 2011 at Howard University.

ENTRY TITLE

Development of Interactive Learning Environment in Classroom by an Innovative Internet based Teaching tool to Improve Faculty Student Interaction

COURSE NUMBER(S) & TITLE(S)

Introduction to Pharmacy (86689-304-01)
Pharmaceutical Sciences Lab (16219-310)
Pharmaceutical Care (86690-305)
Biopharmaceutics (83776-313)
Pharmacokinetics (17497-314)
Pharmaceutics (16216-307)
Colloquim (None)

URL OF RESOURCE

http://classroompresenter.cs.washington.edu/

CDS OR DVDS

The progress of the project is attached as a single poster presentation.

ABSTRACT

Purpose:

The primary objective is to promote active learning in a pharmacy classroom by creating a real-time interactive platform for superior faculty to student communication of Pharmacokinetics, Biopharmaceutics, Pharmaceutical Calculations, Pharmaceutics and Pharmaceutical Lab courses. Parameters such as Improved Faculty-Student Communication, Efficient Delivery of Subject Matter, Improved Student Understanding, Additional Feedback Channels and Improved Student Engagement during a Lecture were evaluated.

Methods:

Faculty and students are equipped with Toshiba Protege tablet laptops with built in wireless adapters. College of Pharmacy is equipped with a 802.11n wireless router for wireless internet access. Classroom Presenter software version 3.1 was employed. Faculty and student tablet computers were bridged via the wi-fi network to enable mutual interaction on the touch interface. Survey monkey analysis integrated with SPSS was employed to obtain confidential evaluation's from the Pharm. D. and Ph.D. students.

Results:

Confidential Survey Monkey analysis data from ~140 student evaluations reported that >90 % of students observed an increase in faculty-student communication, efficient delivery of subject matter, improved engagement and understanding by students compared to the traditional PowerPoint mode in all the courses.

Conclusions:

The technology provided multiple feedback channels providing a dynamic communication platform which promoted faculty-student, student-student and student-faculty real time interaction.

OBJECTIVE/ PROBLEM

Recent advances in technology have made class room teaching more efficient and interesting than ever. Computers and advanced software supported by projection equipment has enabled effective communication of lecture materials to the students. Internet based online resources like BlackboardTM provided the instructor with a medium for efficient distribution of lecture materials and grades to students in a class. Though the current medium provided the College of Pharmacy faculty an effective medium for communication of lecture material to students, it did not allow the students to efficiently communicate real time with faculty. Further, it did not provide a medium where faculty can present an interactive lecture enabling the students to participate and interact in the lecture. The objective of the study is to employ Classroom Presenter technology integrating wireless internet (Wi-Fi) and tablet touch interface providing a real time communication platform resulting in multiple feedback channels for enhanced learning. (Please refer to Figure 1 in the attachment provided)

METHODOLOGY

The current grant proposes to employ Classroom Presenter tool in various classroom lectures taught by the principle investigator (PI) at Howard University, School of Pharmacy. The entire class will be divided into 4-5 groups and tablet PC’s loaded with lecture will be provided to each group. PI will open the PowerPoint lecture on Classroom Presenter and connect the tool with the tool on PC’s distributed to student groups. The PI’s computer will also be connected to the projection system. Digital ink enables the students to write on slides along with faculty. As the lecture progresses, student groups are encouraged participate real time in writing equations, solving problems, presenting images or brief text messages based on their understanding of the lecture. Students are further encouraged to make suggestions (or) additions to the lecture material simultaneously. Please refer to figure 2 in the attachment which demonstrates “Active Learning” and “Real Time Communication” between PI and a student in a demonstration lecture using the proposed technology.

OVERALL EFFECTIVENESS

E-Learn Application – Additional Feedback Channels – Significance:

Classroom Presenter is a web based interaction tool, which will enable the use of digital ink on lecture slides by both faculty and students. Ability to use the digital ink enables combining white board style writing on electronic slides. The most prominent application of the tool is that, faculty can enable a digital link with students in the class. Students can simultaneously add comments on presentation slides along with the faculty. This creates a dynamic learning environment where students interact with faculty real time. Figure 2 is a schematic representing the interactive learning environment created by Classroom Presenter, creating additional feedback channels enabling students to write questions, equations and figures on lecture slides along with the faculty.

LEARNING OUTCOMES

Classroom Presenter provided a “Real time interactive medium” for students to participate in lecture along with faculty.

Classroom Presenter created additional feed back channels, enabling students to interact with fellow classmates and faculty simultaneously.

The technology provided a highly efficient medium for clinical case study demonstration and problem solving in the classroom.

Anonymous evaluations reported significant improvement in overall student learning experience. (Please refer to data of student evaluations from different courses taught by Dr. Pradeep Karla in the attachment)

TEACHING EFFECTIVENESS

The use of this technology significantly improved my interaction with the students and I have noticed a marked increase in student participation and enhanced learning. The technology created a multiple feedback channels which enabled interaction between the students inaddition to the faculty-student interaction. The teaching was significantly effective with the Classroom Presenter technology.

COST-EFFECTIVENESS

Classroom Presenter software is available for download free of cost. This makes adopting the process highly cost effective. All the students in the Pharm.D. program are provided with tablet PC's by the College of Pharmacy.

GENERALIZABILITY

Potential Long-Term Benefits:

1. The web based application can be easily merged with various teaching tools currently being used at Howard University. Hence it can be easily adopted by faculty at Howard University and can have near future and long term benefits.
2. The project will significantly benefit departments like Pharmacy, Computer Science etc. where all the new students are required to have a laptop. Every year, laptops are provided to the first year Pharm.D. students in the school of pharmacy. Given the fact that tablet PC’s are available at a price similar or slightly higher than a regular laptop and the significant impact of innovative teaching medium on the learning process, the proposal can be easily and effectively implemented in near future.

ACCESSIBILITY

The use of this technology need to be further explored for extensive use in students with disabilities. The measurable outcomes of the project are listed below. These outcomes can confer significant advantages to wide set of student population.

1. Addition of this innovative tool to current teaching methods at Howard University can make the method of teaching comprehensive and engaging to students.
2. Classroom Presenter will provide a “Real time interactive medium” for students to participate in lecture along with faculty.
3. Classroom Presenter will create additional feed back channels, enabling students to interact with fellow classmates and faculty simultaneously.

NAME AND EMAIL ADDRESS OF NOMINATOR

Dr. Muhammad J. Habib, mhabib@howard.edu